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Recombinant ZEB1 抗体 (AA 1074-1124)

This anti-ZEB1 antibody is a 兔 单克隆 antibody detecting ZEB1 in WB, FACS 和 IP. Suitable for 人 和 小鼠.
产品编号 ABIN7453320
发货至: 中国

Quick Overview for Recombinant ZEB1 抗体 (AA 1074-1124) (ABIN7453320)

抗原

See all ZEB1 抗体
ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

抗体类型

Recombinant Antibody

适用

  • 55
  • 15
  • 9
  • 6
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  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 41
  • 14
  • 1

克隆类型

  • 29
  • 27
单克隆

标记

  • 43
  • 2
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  • 1
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This ZEB1 antibody is un-conjugated

应用范围

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  • 28
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  • 10
  • 5
  • 3
  • 1
  • 1
  • 1
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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

BLR102H
  • 抗原表位

    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1074-1124

    原理

    Rabbit anti-ZEB1 Recombinant Monoclonal Antibody [BLR102H]

    纯化方法

    Purified

    免疫原

    between AA 1074 and 1124 (C-term)

    亚型

    IgG
  • 应用备注

    IP: 20 μL/1 mg lysate

    WB: 01:01,00

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2 - 8 °C

    有效期

    12 months
  • 抗原

    ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

    别名

    ZEB1

    背景

    ZEB1 (zinc-finger E-box-binding homeobox 1), also known as TCF8 (transcription factor 8), is a delta-EF1/ZFH-1 C2H2-type zinc finger that bears seven C2H2-type zinc fingers and one homeobox DNA-binding domain. ZEB1 is a transcriptional repressor of interleukin-2 (IL-2). Mutations in the ZEB1 gene are associated with posterior corneal dystrophy type 3 (PPC3) a rare disorder characterized by metaplasia and overgrowth of corneal endothelial cells. ZEB1 appears to be critical to epithelial to mesenchymal transitions (EMT) during development and cancer metastasis. As a transcription factor involved in EMT, ZEB1 promotes EMT by repressing genes associated with the epithelial phenotype and activates genes associated with the mesenchymal phenotype.

    基因ID

    6935

    UniProt

    P37275

    途径

    Regulation of Muscle Cell Differentiation
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